Hub of Pregnancy Evaluation (HOPE)

▶ This tool is designed for healthcare professionals and patients with ovarian insufficiency to assess fertility potential and predict pregnancy outcomes. Please see "Predict" for more details.

▶ This tool is developed based on data from the Chinese Ovarian Aging CoHort (COACH). Please see "Introduction" for more details.

PREDICT

What can HOPE do?

Fertility assessment
Perimenopause management
Fertility plan
Mental health guidance
Medication guidance
Long-term health monitoring

Who is HOPE for?

For reproductive-aged women with diminished ovarian function (Basal FSH levels ≥10 IU/L)

The results will serve a valuable reference for guiding fertility planning and developing personalized treatment strategies.

How to predict?

You need to input the necessary information as suggested to generate the FSH trajectory, followed by the pregnancy probability. Please see "Predict" for more details.

We Help You Understand

The global fertility rate continues to decline, while female reproductive aging has emerged as a great challenge on reproductive health worldwide.
In recent years, the increase in social-economic pressure, delayed childbearing, and improved cancer survival, have contributed to a marked increase in the incidence of ovarian insufficiency.

Ovarian Aging-Related Pathologies

Early menopause (EM)
Premature ovarian insufficiency (POl)
Premature ovarian failure (POF)
Diminished ovarian reserve (DOR)
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Causes of Ovarian Aging

Genetic factors
Iatrogenic factors
Immune factors
Environment and other factors
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Symptoms of Ovarian Aging

Irregular menses or amenorrhea
Subfertility or infertility
Osteoporosis
Hypaphrodisia
Vasomotor symptoms
Mood swings
Vaginal dryness
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